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Multiple Myeloma-Derived Extracellular Vesicles Impair Normal Hematopoiesis by Acting on Hematopoietic Stem and Progenitor Cells

Multiple myeloma (MM) is characterized by the abnormal proliferation of clonal plasma cells (PCs) in bone marrow (BM). MM-PCs progressively occupy and likely alter BM niches where reside hematopoietic stem and progenitor cells (HSPCs) whose viability, self-renewal, proliferation, commitment, and dif...

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Detalles Bibliográficos
Autores principales:	Laurenzana, Ilaria, Trino, Stefania, Lamorte, Daniela, De Stradis, Angelo, Santodirocco, Michele, Sgambato, Alessandro, De Luca, Luciana, Caivano, Antonella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716627/ https://www.ncbi.nlm.nih.gov/pubmed/34977093 http://dx.doi.org/10.3389/fmed.2021.793040

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