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The Expression of ephrinA1/ephA2 Receptor Increases in Chronic Rhinosinusitis and ephrinA1/ephA2 Signaling Affects Rhinovirus-Induced Innate Immunity in Human Sinonasal Epithelial Cells

EphA2 receptor and its ephrin ligands are involved in virus infection, epithelial permeability, and chemokine secretion. We hypothesized that ephrinA1/ephA2 signaling participates in rhinovirus (RV)-induced antiviral immune response in sinonasal mucosa of patients with chronic rhinosinusitis (CRS)....

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Detalles Bibliográficos
Autores principales: Lee, Sang Hag, Kang, Sung Hoon, Han, Mun Soo, Kwak, Ji Won, Kim, Hyeon Geun, Lee, Tae Hoon, Lee, Da Bin, Kim, Tae Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716742/
https://www.ncbi.nlm.nih.gov/pubmed/34975898
http://dx.doi.org/10.3389/fimmu.2021.793517