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Gene-Based Testing of Interactions Using XGBoost in Genome-Wide Association Studies

Among the myriad of statistical methods that identify gene–gene interactions in the realm of qualitative genome-wide association studies, gene-based interactions are not only powerful statistically, but also they are interpretable biologically. However, they have limited statistical detection by mak...

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Detalles Bibliográficos
Autores principales: Guo, Yingjie, Wu, Chenxi, Yuan, Zhian, Wang, Yansu, Liang, Zhen, Wang, Yang, Zhang, Yi, Xu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716787/
https://www.ncbi.nlm.nih.gov/pubmed/34977040
http://dx.doi.org/10.3389/fcell.2021.801113