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PDE4B Induces Epithelial-to-Mesenchymal Transition in Bladder Cancer Cells and Is Transcriptionally Suppressed by CBX7

Urinary bladder cancer (UBC) is a common malignant tumor with high incidence. Advances in the diagnosis and treatment of this disease demand the identification of novel therapeutic targets. Multiple studies demonstrated that PDE4B level was upregulated in malignancies and high PDE4B expression was c...

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Detalles Bibliográficos
Autores principales: Huang, Zhengnan, Liu, Jiakuan, Yang, Jiale, Yan, Yilin, Yang, Chenkai, He, Xiao, Huang, Ruimin, Tan, Mingyue, Wu, Denglong, Yan, Jun, Shen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716816/
https://www.ncbi.nlm.nih.gov/pubmed/34977026
http://dx.doi.org/10.3389/fcell.2021.783050