Case Report: Identification of Multiple TERT and FGFR2 Gene Fusions in a Pineal Region Glioblastoma Case

As an oncogenic somatic variant, telomerase reverse transcriptase promoter (TERTp) mutations are frequently observed in adult glioblastoma (GBM). Alternatively, we report the first case of glioblastoma with TERT amplification accompanied by multiple TERT and FGFR2 gene fusions instead of TERTp mutat...

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Detalles Bibliográficos
Autores principales: Guo, Xing, Chen, Teng, Chen, Shiming, Song, Chao, Shan, Dezhi, Xu, Shujun, Xu, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716851/
https://www.ncbi.nlm.nih.gov/pubmed/34976798
http://dx.doi.org/10.3389/fonc.2021.739309

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