A rare etiology of persistent jaundice in type 1 autoimmune hepatitis

A 24-year-old male without previously known comorbidities presented with progressive jaundice and hepatomegaly. Autoimmune serology and liver biopsy revealed features of autoimmune hepatitis. A treatment by oral prednisolone and azathioprine was initiated, after which he achieved remission. However,...

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Autores principales: Kumar, Budumuri Gautam V., Sethy, Purna Ch., Gupta, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: UMF “Gr. T. Popa” Iasi Publishing House 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717003/
https://www.ncbi.nlm.nih.gov/pubmed/34984223
http://dx.doi.org/10.22551/2021.32.0803.10183
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author Kumar, Budumuri Gautam V.
Sethy, Purna Ch.
Gupta, Rohit
author_facet Kumar, Budumuri Gautam V.
Sethy, Purna Ch.
Gupta, Rohit
author_sort Kumar, Budumuri Gautam V.
collection PubMed
description A 24-year-old male without previously known comorbidities presented with progressive jaundice and hepatomegaly. Autoimmune serology and liver biopsy revealed features of autoimmune hepatitis. A treatment by oral prednisolone and azathioprine was initiated, after which he achieved remission. However, hyperbilirubinemia persisted, with a predominantly unconjugated fraction. Hemolytic causes of unconjugated hyperbilirubinemia were ruled out, and the diagnosis of Gilbert syndrome was established.
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spelling pubmed-87170032022-01-03 A rare etiology of persistent jaundice in type 1 autoimmune hepatitis Kumar, Budumuri Gautam V. Sethy, Purna Ch. Gupta, Rohit Arch Clin Cases Case Report A 24-year-old male without previously known comorbidities presented with progressive jaundice and hepatomegaly. Autoimmune serology and liver biopsy revealed features of autoimmune hepatitis. A treatment by oral prednisolone and azathioprine was initiated, after which he achieved remission. However, hyperbilirubinemia persisted, with a predominantly unconjugated fraction. Hemolytic causes of unconjugated hyperbilirubinemia were ruled out, and the diagnosis of Gilbert syndrome was established. UMF “Gr. T. Popa” Iasi Publishing House 2021-12-29 /pmc/articles/PMC8717003/ /pubmed/34984223 http://dx.doi.org/10.22551/2021.32.0803.10183 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kumar, Budumuri Gautam V.
Sethy, Purna Ch.
Gupta, Rohit
A rare etiology of persistent jaundice in type 1 autoimmune hepatitis
title A rare etiology of persistent jaundice in type 1 autoimmune hepatitis
title_full A rare etiology of persistent jaundice in type 1 autoimmune hepatitis
title_fullStr A rare etiology of persistent jaundice in type 1 autoimmune hepatitis
title_full_unstemmed A rare etiology of persistent jaundice in type 1 autoimmune hepatitis
title_short A rare etiology of persistent jaundice in type 1 autoimmune hepatitis
title_sort rare etiology of persistent jaundice in type 1 autoimmune hepatitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717003/
https://www.ncbi.nlm.nih.gov/pubmed/34984223
http://dx.doi.org/10.22551/2021.32.0803.10183
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