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Secondary thyroid malignancy – a rare clinical finding?

Metastases to the thyroid gland, while rarely seen in clinical practice, can pose a diagnostic and therapeutic challenge. Most commonly, they originate from lung, renal, and breast cancer, and are generally a sign of multiorgan metastatic disease. In most cases, metastases to the thyroid gland are d...

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Autores principales: Mitrache, Marius-Lucian, Zubașcu, Gheorghiță Patriciu, Dumitraș, Teodor, Martin, Carmen Sorina, Fica, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: UMF “Gr. T. Popa” Iasi Publishing House 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717008/
https://www.ncbi.nlm.nih.gov/pubmed/34984232
http://dx.doi.org/10.22551/2021.33.0804.10192
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author Mitrache, Marius-Lucian
Zubașcu, Gheorghiță Patriciu
Dumitraș, Teodor
Martin, Carmen Sorina
Fica, Simona
author_facet Mitrache, Marius-Lucian
Zubașcu, Gheorghiță Patriciu
Dumitraș, Teodor
Martin, Carmen Sorina
Fica, Simona
author_sort Mitrache, Marius-Lucian
collection PubMed
description Metastases to the thyroid gland, while rarely seen in clinical practice, can pose a diagnostic and therapeutic challenge. Most commonly, they originate from lung, renal, and breast cancer, and are generally a sign of multiorgan metastatic disease. In most cases, metastases to the thyroid gland are diagnosed incidentally on imaging studies, since they are rarely symptomatic and often do not influence thyroid function tests. Thyroid ultrasonography and fine-needle aspiration biopsy play a pivotal role in their evaluation, as both classic immunocytochemical features, and more novel molecular markers can help in the differential diagnosis. Prognosis mainly depends on the biology of the primary tumor and its extension. Communication between clinicians is essential in such patients, in order to ensure that the treatment options are carefully balanced, thus raising the need for multidisciplinary teams in their management.
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spelling pubmed-87170082022-01-03 Secondary thyroid malignancy – a rare clinical finding? Mitrache, Marius-Lucian Zubașcu, Gheorghiță Patriciu Dumitraș, Teodor Martin, Carmen Sorina Fica, Simona Arch Clin Cases Review Metastases to the thyroid gland, while rarely seen in clinical practice, can pose a diagnostic and therapeutic challenge. Most commonly, they originate from lung, renal, and breast cancer, and are generally a sign of multiorgan metastatic disease. In most cases, metastases to the thyroid gland are diagnosed incidentally on imaging studies, since they are rarely symptomatic and often do not influence thyroid function tests. Thyroid ultrasonography and fine-needle aspiration biopsy play a pivotal role in their evaluation, as both classic immunocytochemical features, and more novel molecular markers can help in the differential diagnosis. Prognosis mainly depends on the biology of the primary tumor and its extension. Communication between clinicians is essential in such patients, in order to ensure that the treatment options are carefully balanced, thus raising the need for multidisciplinary teams in their management. UMF “Gr. T. Popa” Iasi Publishing House 2021-12-29 /pmc/articles/PMC8717008/ /pubmed/34984232 http://dx.doi.org/10.22551/2021.33.0804.10192 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Mitrache, Marius-Lucian
Zubașcu, Gheorghiță Patriciu
Dumitraș, Teodor
Martin, Carmen Sorina
Fica, Simona
Secondary thyroid malignancy – a rare clinical finding?
title Secondary thyroid malignancy – a rare clinical finding?
title_full Secondary thyroid malignancy – a rare clinical finding?
title_fullStr Secondary thyroid malignancy – a rare clinical finding?
title_full_unstemmed Secondary thyroid malignancy – a rare clinical finding?
title_short Secondary thyroid malignancy – a rare clinical finding?
title_sort secondary thyroid malignancy – a rare clinical finding?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717008/
https://www.ncbi.nlm.nih.gov/pubmed/34984232
http://dx.doi.org/10.22551/2021.33.0804.10192
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