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Magnetic challenge against gastroesophageal reflux

Almost 15 years have passed since the first paper on the possibility of using magnets to prevent gastro-esophageal reflux (GER) was published and so it is time to assess the results obtained with the first magnetic device available on the market, the Linx magnetic sphincter augmentation (MSA) and to...

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Autor principal: Bortolotti, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717015/
https://www.ncbi.nlm.nih.gov/pubmed/35068867
http://dx.doi.org/10.3748/wjg.v27.i48.8227
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author Bortolotti, Mauro
author_facet Bortolotti, Mauro
author_sort Bortolotti, Mauro
collection PubMed
description Almost 15 years have passed since the first paper on the possibility of using magnets to prevent gastro-esophageal reflux (GER) was published and so it is time to assess the results obtained with the first magnetic device available on the market, the Linx magnetic sphincter augmentation (MSA) and to consider what other options are forthcoming. MSA demonstrated an anti-reflux activity similar to that of Nissen fundoplication, considered the “gold standard” surgical treatment for GER disease, and caused less gas-bloating and a better ability to allow vomiting and belching. However, unlike Nissen fundoplication, this magnetic device is burdened by complications, which are roughly similar to those of the non-magnetic anti-reflux Angelchik prosthesis, that, after considerable use in the eighties, was shelved due to these complications. It is interesting to note that some of these complications show the same pathophysiological mechanism in both devices. The upcoming new magnetic devices should avoid these complications, as their anti-reflux magnetic mechanism is completely different. The experiments in animals regarding these new magnetic appliances were examined, remarking their advantages and drawbacks, but the way to apply them in surgical practice is long and difficult, although worthy, as they represent the future of magnetic surgery.
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spelling pubmed-87170152022-01-20 Magnetic challenge against gastroesophageal reflux Bortolotti, Mauro World J Gastroenterol Frontier Almost 15 years have passed since the first paper on the possibility of using magnets to prevent gastro-esophageal reflux (GER) was published and so it is time to assess the results obtained with the first magnetic device available on the market, the Linx magnetic sphincter augmentation (MSA) and to consider what other options are forthcoming. MSA demonstrated an anti-reflux activity similar to that of Nissen fundoplication, considered the “gold standard” surgical treatment for GER disease, and caused less gas-bloating and a better ability to allow vomiting and belching. However, unlike Nissen fundoplication, this magnetic device is burdened by complications, which are roughly similar to those of the non-magnetic anti-reflux Angelchik prosthesis, that, after considerable use in the eighties, was shelved due to these complications. It is interesting to note that some of these complications show the same pathophysiological mechanism in both devices. The upcoming new magnetic devices should avoid these complications, as their anti-reflux magnetic mechanism is completely different. The experiments in animals regarding these new magnetic appliances were examined, remarking their advantages and drawbacks, but the way to apply them in surgical practice is long and difficult, although worthy, as they represent the future of magnetic surgery. Baishideng Publishing Group Inc 2021-12-28 2021-12-28 /pmc/articles/PMC8717015/ /pubmed/35068867 http://dx.doi.org/10.3748/wjg.v27.i48.8227 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Frontier
Bortolotti, Mauro
Magnetic challenge against gastroesophageal reflux
title Magnetic challenge against gastroesophageal reflux
title_full Magnetic challenge against gastroesophageal reflux
title_fullStr Magnetic challenge against gastroesophageal reflux
title_full_unstemmed Magnetic challenge against gastroesophageal reflux
title_short Magnetic challenge against gastroesophageal reflux
title_sort magnetic challenge against gastroesophageal reflux
topic Frontier
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717015/
https://www.ncbi.nlm.nih.gov/pubmed/35068867
http://dx.doi.org/10.3748/wjg.v27.i48.8227
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