Sustained experimental activation of FGF8/ERK in the developing chicken spinal cord models early events in ERK-mediated tumorigenesis

The MAPK/ERK pathway regulates a variety of physiological cellular functions, including cell proliferation and survival. It is abnormally activated in many types of human cancers in response to driver mutations in regulators of this pathway that trigger tumor initiation. The early steps of oncogenic...

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Detalles Bibliográficos
Autores principales: Wilmerding, Axelle, Bouteille, Lauranne, Caruso, Nathalie, Bidaut, Ghislain, Etchevers, Heather C., Graba, Yacine, Delfini, Marie-Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717438/
https://www.ncbi.nlm.nih.gov/pubmed/34959031
http://dx.doi.org/10.1016/j.neo.2021.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717438/
https://www.ncbi.nlm.nih.gov/pubmed/34959031
http://dx.doi.org/10.1016/j.neo.2021.12.006

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