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Solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: A case report
BACKGROUND: Solid pseudopapillary neoplasms (SPNs) are rare tumors of the pancreas. Typically, they occur in young females, often have characteristic imaging features, such as cystic components and calcification, and have few effects on the pancreatic duct. CASE SUMMARY: A 31-year-old man was admitt...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717495/ https://www.ncbi.nlm.nih.gov/pubmed/35071569 http://dx.doi.org/10.12998/wjcc.v9.i36.11382 |
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author | Nakashima, Saki Sato, Yoshiki Imamura, Tsunao Hattori, Daisuke Tamura, Tetsuo Koyama, Rikako Sato, Junichiro Kobayashi, Yuta Hashimoto, Masaji |
author_facet | Nakashima, Saki Sato, Yoshiki Imamura, Tsunao Hattori, Daisuke Tamura, Tetsuo Koyama, Rikako Sato, Junichiro Kobayashi, Yuta Hashimoto, Masaji |
author_sort | Nakashima, Saki |
collection | PubMed |
description | BACKGROUND: Solid pseudopapillary neoplasms (SPNs) are rare tumors of the pancreas. Typically, they occur in young females, often have characteristic imaging features, such as cystic components and calcification, and have few effects on the pancreatic duct. CASE SUMMARY: A 31-year-old man was admitted to our hospital with the chief complaint of epigastric pain. There was only mild tenderness in his upper abdomen, and blood tests showed only a slight increase in alkaline phosphatase. Contrast-enhanced computed tomography showed a 40-mm-diameter, hypovascular mass in the head of the pancreas, and the main pancreatic duct upstream of the mass was severely dilated. Magnetic resonance imaging showed low intensity on T1-weighted images, with high intensity on T2-weighted image in some parts. Pancreatic ductal adenocarcinoma was the primary differential diagnosis. Portal vein infiltration could not be ruled out, so this case was a candidate for neoadjuvant chemotherapy. Subsequently, endoscopic ultrasound-guided fine needle aspiration was performed, and pathological evaluation and immunostaining suggested a diagnosis of SPN. Thus, pancreatoduodenectomy was performed. One year after the operation, the patient is alive with no recurrence. CONCLUSION: Main pancreatic duct dilatation is usually a finding of suspected pancreatic cancer. However, pancreatic duct dilatation can occur in SPN depending on the location and growth speed. Therefore, SPN should be considered in the differential diagnosis of tumors with pancreatic duct dilatation, and pathological evaluation by endoscopic ultrasound-guided fine needle aspiration should be actively performed. |
format | Online Article Text |
id | pubmed-8717495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-87174952022-01-20 Solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: A case report Nakashima, Saki Sato, Yoshiki Imamura, Tsunao Hattori, Daisuke Tamura, Tetsuo Koyama, Rikako Sato, Junichiro Kobayashi, Yuta Hashimoto, Masaji World J Clin Cases Case Report BACKGROUND: Solid pseudopapillary neoplasms (SPNs) are rare tumors of the pancreas. Typically, they occur in young females, often have characteristic imaging features, such as cystic components and calcification, and have few effects on the pancreatic duct. CASE SUMMARY: A 31-year-old man was admitted to our hospital with the chief complaint of epigastric pain. There was only mild tenderness in his upper abdomen, and blood tests showed only a slight increase in alkaline phosphatase. Contrast-enhanced computed tomography showed a 40-mm-diameter, hypovascular mass in the head of the pancreas, and the main pancreatic duct upstream of the mass was severely dilated. Magnetic resonance imaging showed low intensity on T1-weighted images, with high intensity on T2-weighted image in some parts. Pancreatic ductal adenocarcinoma was the primary differential diagnosis. Portal vein infiltration could not be ruled out, so this case was a candidate for neoadjuvant chemotherapy. Subsequently, endoscopic ultrasound-guided fine needle aspiration was performed, and pathological evaluation and immunostaining suggested a diagnosis of SPN. Thus, pancreatoduodenectomy was performed. One year after the operation, the patient is alive with no recurrence. CONCLUSION: Main pancreatic duct dilatation is usually a finding of suspected pancreatic cancer. However, pancreatic duct dilatation can occur in SPN depending on the location and growth speed. Therefore, SPN should be considered in the differential diagnosis of tumors with pancreatic duct dilatation, and pathological evaluation by endoscopic ultrasound-guided fine needle aspiration should be actively performed. Baishideng Publishing Group Inc 2021-12-26 2021-12-26 /pmc/articles/PMC8717495/ /pubmed/35071569 http://dx.doi.org/10.12998/wjcc.v9.i36.11382 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Nakashima, Saki Sato, Yoshiki Imamura, Tsunao Hattori, Daisuke Tamura, Tetsuo Koyama, Rikako Sato, Junichiro Kobayashi, Yuta Hashimoto, Masaji Solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: A case report |
title | Solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: A case report |
title_full | Solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: A case report |
title_fullStr | Solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: A case report |
title_full_unstemmed | Solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: A case report |
title_short | Solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: A case report |
title_sort | solid pseudopapillary neoplasm of the pancreas in a young male with main pancreatic duct dilatation: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717495/ https://www.ncbi.nlm.nih.gov/pubmed/35071569 http://dx.doi.org/10.12998/wjcc.v9.i36.11382 |
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