FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis

BACKGROUND: Ferroptosis is a newly identified type of programmed cell death, which preferentially targets iron-rich cancer cells such as hepatocellular carcinoma (HCC). Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to preve...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Wanye, Zhou, Chaoting, Jing, Qiangan, Li, Yancun, Yang, Jing, Yang, Chen, Wang, Luyang, Hu, Jiayu, Li, Huanjuan, Wang, Hairui, Yuan, Chen, Zhou, Yi, Ren, Xueying, Tong, Xiangmin, Du, Jing, Wang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717654/
https://www.ncbi.nlm.nih.gov/pubmed/34965856
http://dx.doi.org/10.1186/s12935-021-02420-x

Ejemplares similares

Ejemplares similares