Cargando…

Plasma from healthy donors protects blood–brain barrier integrity via FGF21 and improves the recovery in a mouse model of cerebral ischaemia

BACKGROUND: Healthy plasma therapy reverses cognitive deficits and promotes neuroplasticity in ageing brain disease. However, whether healthy plasma therapy improve blood–brain barrier integrity after stroke remains unknown. METHODS: Here, we intravenously injected healthy female mouse plasma into a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mamtilahun, Muyassar, Jiang, Lu, Song, Yaying, Shi, Xiaojing, Liu, Chang, Jiang, Yixu, Deng, Lidong, Zheng, Haoran, Shen, Hui, Li, Yongfang, Zhang, Zhijun, Wang, Yongting, Tang, Yaohui, Yang, Guo-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717795/ https://www.ncbi.nlm.nih.gov/pubmed/33785536 http://dx.doi.org/10.1136/svn-2020-000774

Ejemplares similares

M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice
por: Li, Yongfang, et al.
Publicado: (2022)

Fingolimod Inhibits Inflammation but Exacerbates Brain Edema in the Acute Phases of Cerebral Ischemia in Diabetic Mice
por: Li, Wanlu, et al.
Publicado: (2020)

DL-3n-Butylphthalide Improves Blood–Brain Barrier Integrity in Rat After Middle Cerebral Artery Occlusion
por: Mamtilahun, Muyassar, et al.
Publicado: (2021)

Endothelial progenitor cells transplantation attenuated blood-brain barrier damage after ischemia in diabetic mice via HIF-1α
por: Geng, Jieli, et al.
Publicado: (2017)

Extracellular vesicles from adipose-derived stem cells promote microglia M2 polarization and neurological recovery in a mouse model of transient middle cerebral artery occlusion
por: Hu, Xiaowen, et al.
Publicado: (2022)

Stroke subtype-dependent synapse elimination by reactive gliosis in mice
por: Shi, Xiaojing, et al.
Publicado: (2021)

Author Correction: Stroke subtype-dependent synapse elimination by reactive gliosis in mice
por: Shi, Xiaojing, et al.
Publicado: (2022)

Transcranial Focused Ultrasound Stimulation Improves Neurorehabilitation after Middle Cerebral Artery Occlusion in Mice
por: Wang, Jixian, et al.
Publicado: (2021)

Oligodendrocyte Precursor Cells Transplantation Improves Stroke Recovery via Oligodendrogenesis, Neurite Growth and Synaptogenesis
por: Li, Wanlu, et al.
Publicado: (2021)

Farnesoid X receptor knockout protects brain against ischemic injury through reducing neuronal apoptosis in mice
por: Shan, Hui-Min, et al.
Publicado: (2020)

Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion
por: Zhang, Lin-Yuan, et al.
Publicado: (2020)

MicroRNA-126 Regulates Angiogenesis and Neurogenesis in a Mouse Model of Focal Cerebral Ischemia
por: Qu, Meijie, et al.
Publicado: (2019)

Sensitive imaging of intact microvessels in vivo with synchrotron radiation
por: Wang, Feixiang, et al.
Publicado: (2020)

M2 microglia-derived exosomes protect the mouse brain from ischemia-reperfusion injury via exosomal miR-124
por: Song, Yaying, et al.
Publicado: (2019)

FGF19 subfamily members: FGF19 and FGF21
por: Dolegowska, Katarzyna, et al.
Publicado: (2019)

Blocking C3d(+)/GFAP(+) A1 Astrocyte Conversion with Semaglutide Attenuates Blood-Brain Barrier Disruption in Mice after Ischemic Stroke
por: Zhang, Qi, et al.
Publicado: (2022)

M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 pathway after ischemic stroke in mice
por: Li, Zongwei, et al.
Publicado: (2021)

Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice
por: Cheng, Zhuo, et al.
Publicado: (2018)

FGF19 and FGF21: In NASH we trust
por: Talukdar, Saswata, et al.
Publicado: (2020)

FGF21 and Cardiac Physiopathology
por: Planavila, Anna, et al.
Publicado: (2015)

Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
por: Adams, Andrew C., et al.
Publicado: (2012)

FGF19 and FGF21 for the Treatment of NASH—Two Sides of the Same Coin? Differential and Overlapping Effects of FGF19 and FGF21 From Mice to Human
por: Henriksson, Emma, et al.
Publicado: (2020)

Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue
por: Villarroya, Joan, et al.
Publicado: (2018)

Association between FGF19, FGF21 and lipocalin-2, and diabetes progression in PCOS
por: Cheng, Feifei, et al.
Publicado: (2021)

Fibroblast Growth Factor 21 (FGF21) in Human Cerebrospinal Fluid: Relationship With Plasma FGF21 and Body Adiposity
por: Tan, Bee K., et al.
Publicado: (2011)

Neurovascular Recovery via Cotransplanted Neural and Vascular Progenitors Leads to Improved Functional Restoration after Ischemic Stroke in Rats
por: Li, Jia, et al.
Publicado: (2014)

FGF21 as a Stress Hormone: The Roles of FGF21 in Stress Adaptation and the Treatment of Metabolic Diseases
por: Kim, Kook Hwan, et al.
Publicado: (2014)

Blood-Brain Barrier Disruption Induced Cognitive Impairment Is Associated With Increase of Inflammatory Cytokine
por: Geng, Jieli, et al.
Publicado: (2018)

Head Over Hepatocytes for FGF21
por: Potthoff, Matthew J., et al.
Publicado: (2014)

Analysis of Functional Promoter of Camel FGF21 Gene and Identification of Small Compounds Targeting FGF21 Protein
por: Yong, Fang, et al.
Publicado: (2023)

Lower Cerebrospinal Fluid/Plasma Fibroblast Growth Factor 21 (FGF21) Ratios and Placental FGF21 Production in Gestational Diabetes
por: Tan, Bee K., et al.
Publicado: (2013)

The Suitability of FGF21 and FGF23 as New Biomarkers in Endometrial Cancer Patients
por: Cymbaluk-Płoska, Aneta, et al.
Publicado: (2020)

Biological and pharmacological functions of the FGF19- and FGF21-coreceptor beta klotho
por: Aaldijk, Alexandra S., et al.
Publicado: (2023)

Paradoxical Regulation of Human FGF21 by Both Fasting and Feeding Signals: Is FGF21 a Nutritional Adaptation Factor?
por: Uebanso, Takashi, et al.
Publicado: (2011)

Targeted delivery of fat extract by platelet membrane-cloaked nanocarriers for the treatment of ischemic stroke
por: Wang, Cheng, et al.
Publicado: (2022)

FGF21 Protects Against Hypoxia Injury Through Inducing HSP72 in Cerebral Microvascular Endothelial Cells
por: Wang, Hao-Wei, et al.
Publicado: (2019)

Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity
por: Agrawal, Archita, et al.
Publicado: (2018)

Inventing new medicines: The FGF21 story()
por: Kharitonenkov, Alexei, et al.
Publicado: (2013)

The good, the bad, and the unknown: Fructose and FGF21()
por: Hofmann, Susanna M., et al.
Publicado: (2014)

Metabolic Effects of FGF-21: Thermoregulation and Beyond
por: Ni, Bin, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_sm7nc9iscc4t0mapt0780uvcg4