Oncogenic Activation of YAP Signaling Sensitizes Ferroptosis of Hepatocellular Carcinoma via ALOXE3-Mediated Lipid Peroxidation Accumulation

Ferroptosis, a form of programmed cell death process driven by iron-dependent lipid peroxidation, plays an important role in tumor suppression. Although previous study showed that intracellular Merlin-Hippo signaling suppresses ferroptosis of epithelial tumor cells through the inactivation of YAP si...

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Detalles Bibliográficos
Autores principales: Qin, Yifei, Pei, Zhuo, Feng, Zhuan, Lin, Peng, Wang, Shijie, Li, Yong, Huo, Fei, Wang, Quancheng, Wang, Zhiping, Chen, Zhi-Nan, Wu, Jiao, Wang, Yi-Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717939/
https://www.ncbi.nlm.nih.gov/pubmed/34977009
http://dx.doi.org/10.3389/fcell.2021.751593

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