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Comparison of RNA synthesis initiation properties of non-segmented negative strand RNA virus polymerases

It is generally thought that the promoters of non-segmented, negative strand RNA viruses (nsNSVs) direct the polymerase to initiate RNA synthesis exclusively opposite the 3´ terminal nucleotide of the genome RNA by a de novo (primer independent) initiation mechanism. However, recent studies have rev...

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Detalles Bibliográficos
Autores principales: Shareef, Afzaal M., Ludeke, Barbara, Jordan, Paul, Deval, Jerome, Fearns, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717993/
https://www.ncbi.nlm.nih.gov/pubmed/34914795
http://dx.doi.org/10.1371/journal.ppat.1010151