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Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes

BACKGROUND: Skeletal muscle as a metabolic consumer determines systemic energy homeostasis by regulating myofibre type conversion and muscle mass control. Perturbation of the skeletal muscle metabolism elevates the risk of a variety of diseases including metabolic disorders. However, the regulatory...

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Detalles Bibliográficos
Autores principales: Kim, Ayoung, Koo, Ja Hyun, Jin, Xing, Kim, Wondong, Park, Shi‐Young, Park, Sunghyouk, Rhee, Eugene P., Choi, Cheol Soo, Kim, Sang Geon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718070/
https://www.ncbi.nlm.nih.gov/pubmed/34523817
http://dx.doi.org/10.1002/jcsm.12777