Pim1 knockout alleviates sarcopenia in aging mice via reducing adipogenic differentiation of PDGFRα(+) mesenchymal progenitors

BACKGROUND: Sarcopenia widely exists in elderly people and triggers numerous age‐related events. The essential pathologic change lies in the increased intramuscular adipose tissue after aging with no exception to non‐obese objects. Pim1 appears to be associated with adipogenic differentiation in rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Shang, Guo‐kai, Han, Lu, Wang, Zhi‐hao, Song, Ming, Wang, Di, Tan, Yan‐min, Li, Yi‐hui, Li, Yu‐lin, Zhang, Wei, Zhong, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718082/
https://www.ncbi.nlm.nih.gov/pubmed/34435457
http://dx.doi.org/10.1002/jcsm.12770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718082/
https://www.ncbi.nlm.nih.gov/pubmed/34435457
http://dx.doi.org/10.1002/jcsm.12770

Ejemplares similares