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Pim1 knockout alleviates sarcopenia in aging mice via reducing adipogenic differentiation of PDGFRα(+) mesenchymal progenitors
BACKGROUND: Sarcopenia widely exists in elderly people and triggers numerous age‐related events. The essential pathologic change lies in the increased intramuscular adipose tissue after aging with no exception to non‐obese objects. Pim1 appears to be associated with adipogenic differentiation in rec...
Autores principales: | Shang, Guo‐kai, Han, Lu, Wang, Zhi‐hao, Song, Ming, Wang, Di, Tan, Yan‐min, Li, Yi‐hui, Li, Yu‐lin, Zhang, Wei, Zhong, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718082/ https://www.ncbi.nlm.nih.gov/pubmed/34435457 http://dx.doi.org/10.1002/jcsm.12770 |
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