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The role of 15 lipoxygenase 1 in asthma comes into focus
IL-4– and IL-13–driven epithelial cell expression of 15 lipoxygenase 1 (15LO1) is a consistent feature of eosinophil-dominated asthma known as type 2–high (T2-high) asthma. The abundant soluble products of arachidonic acid (AA) metabolized by 15LO1 reflect a high level of enzymatic activity in asthm...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Clinical Investigation
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718133/ https://www.ncbi.nlm.nih.gov/pubmed/34981786 http://dx.doi.org/10.1172/JCI155884 |