The CD6/ALCAM pathway promotes lupus nephritis via T cell–mediated responses

T cells are central to the pathogenesis of lupus nephritis (LN), a common complication of systemic lupus erythematosus (SLE). CD6 and its ligand, activated leukocyte cell adhesion molecule (ALCAM), are involved in T cell activation and trafficking. Previously, we showed that soluble ALCAM is increas...

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Detalles Bibliográficos
Autores principales: Chalmers, Samantha A., Ayilam Ramachandran, Rajalakshmy, Garcia, Sayra J., Der, Evan, Herlitz, Leal, Ampudia, Jeanette, Chu, Dalena, Jordan, Nicole, Zhang, Ting, Parodis, Ioannis, Gunnarsson, Iva, Ding, Huihua, Shen, Nan, Petri, Michelle, Mok, Chi Chiu, Saxena, Ramesh, Polu, Krishna R., Connelly, Stephen, Ng, Cherie T., Mohan, Chandra, Putterman, Chaim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718154/
https://www.ncbi.nlm.nih.gov/pubmed/34981775
http://dx.doi.org/10.1172/JCI147334

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