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cGAS‒STING signaling and function in metabolism and kidney diseases

The cyclic GMP‒AMP synthase (cGAS)‒stimulator of interferon genes (STING) signaling pathway senses the presence of cytosolic DNA and, in turn, triggers downstream signaling to induce the expression of inflammatory and type I interferon genes in immune cells. Whereas the innate immune function of the...

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Detalles Bibliográficos
Autores principales: Bai, Juli, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718186/
https://www.ncbi.nlm.nih.gov/pubmed/34665236
http://dx.doi.org/10.1093/jmcb/mjab066