Cargando…

Massive Calcified Epithelioid Hemangioendothelioma With Multifocal Involvement: An Imaging Diagnosis Dilemma and a Rare Case Report

Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular tumor that develops from vascular endothelial or pre-endothelial cells. More than 60% patients have single-organ involvement, and involvement of multiple organs including the liver, lungs, and bones is extremely rare. The typical ra...

Descripción completa

Detalles Bibliográficos
Autores principales: Che, Feng, Yang, Cai wei, Hu, Xue, Li, Qian, Wei, Yi, Liu, Xi jiao, Song, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718394/
https://www.ncbi.nlm.nih.gov/pubmed/34976822
http://dx.doi.org/10.3389/fonc.2021.782970
_version_ 1784624714878025728
author Che, Feng
Yang, Cai wei
Hu, Xue
Li, Qian
Wei, Yi
Liu, Xi jiao
Song, Bin
author_facet Che, Feng
Yang, Cai wei
Hu, Xue
Li, Qian
Wei, Yi
Liu, Xi jiao
Song, Bin
author_sort Che, Feng
collection PubMed
description Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular tumor that develops from vascular endothelial or pre-endothelial cells. More than 60% patients have single-organ involvement, and involvement of multiple organs including the liver, lungs, and bones is extremely rare. The typical radiographic features of EHE include multiple small nodules in both lungs, which are usually located near small- and medium-sized blood vessels and the bronchi, and solitary, multiple, or diffuse lesions located at the hepatic periphery, spreading within the branches of the portal and hepatic veins. Radiologic calcification has been rarely reported in the literature. Here, we firstly described a case of a 53-year-old woman with EHE who presented with lungs, liver, bone, and right hilar lymph node involvement, manifesting as massive calcification on computed tomography. This case reminds physicians that EHE may present with unusual imaging manifestations, like massive calcification, and should be considered during the diagnostic process.
format Online
Article
Text
id pubmed-8718394
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-87183942022-01-01 Massive Calcified Epithelioid Hemangioendothelioma With Multifocal Involvement: An Imaging Diagnosis Dilemma and a Rare Case Report Che, Feng Yang, Cai wei Hu, Xue Li, Qian Wei, Yi Liu, Xi jiao Song, Bin Front Oncol Oncology Epithelioid hemangioendothelioma (EHE) is a rare malignant vascular tumor that develops from vascular endothelial or pre-endothelial cells. More than 60% patients have single-organ involvement, and involvement of multiple organs including the liver, lungs, and bones is extremely rare. The typical radiographic features of EHE include multiple small nodules in both lungs, which are usually located near small- and medium-sized blood vessels and the bronchi, and solitary, multiple, or diffuse lesions located at the hepatic periphery, spreading within the branches of the portal and hepatic veins. Radiologic calcification has been rarely reported in the literature. Here, we firstly described a case of a 53-year-old woman with EHE who presented with lungs, liver, bone, and right hilar lymph node involvement, manifesting as massive calcification on computed tomography. This case reminds physicians that EHE may present with unusual imaging manifestations, like massive calcification, and should be considered during the diagnostic process. Frontiers Media S.A. 2021-12-17 /pmc/articles/PMC8718394/ /pubmed/34976822 http://dx.doi.org/10.3389/fonc.2021.782970 Text en Copyright © 2021 Che, Yang, Hu, Li, Wei, Liu and Song https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Che, Feng
Yang, Cai wei
Hu, Xue
Li, Qian
Wei, Yi
Liu, Xi jiao
Song, Bin
Massive Calcified Epithelioid Hemangioendothelioma With Multifocal Involvement: An Imaging Diagnosis Dilemma and a Rare Case Report
title Massive Calcified Epithelioid Hemangioendothelioma With Multifocal Involvement: An Imaging Diagnosis Dilemma and a Rare Case Report
title_full Massive Calcified Epithelioid Hemangioendothelioma With Multifocal Involvement: An Imaging Diagnosis Dilemma and a Rare Case Report
title_fullStr Massive Calcified Epithelioid Hemangioendothelioma With Multifocal Involvement: An Imaging Diagnosis Dilemma and a Rare Case Report
title_full_unstemmed Massive Calcified Epithelioid Hemangioendothelioma With Multifocal Involvement: An Imaging Diagnosis Dilemma and a Rare Case Report
title_short Massive Calcified Epithelioid Hemangioendothelioma With Multifocal Involvement: An Imaging Diagnosis Dilemma and a Rare Case Report
title_sort massive calcified epithelioid hemangioendothelioma with multifocal involvement: an imaging diagnosis dilemma and a rare case report
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718394/
https://www.ncbi.nlm.nih.gov/pubmed/34976822
http://dx.doi.org/10.3389/fonc.2021.782970
work_keys_str_mv AT chefeng massivecalcifiedepithelioidhemangioendotheliomawithmultifocalinvolvementanimagingdiagnosisdilemmaandararecasereport
AT yangcaiwei massivecalcifiedepithelioidhemangioendotheliomawithmultifocalinvolvementanimagingdiagnosisdilemmaandararecasereport
AT huxue massivecalcifiedepithelioidhemangioendotheliomawithmultifocalinvolvementanimagingdiagnosisdilemmaandararecasereport
AT liqian massivecalcifiedepithelioidhemangioendotheliomawithmultifocalinvolvementanimagingdiagnosisdilemmaandararecasereport
AT weiyi massivecalcifiedepithelioidhemangioendotheliomawithmultifocalinvolvementanimagingdiagnosisdilemmaandararecasereport
AT liuxijiao massivecalcifiedepithelioidhemangioendotheliomawithmultifocalinvolvementanimagingdiagnosisdilemmaandararecasereport
AT songbin massivecalcifiedepithelioidhemangioendotheliomawithmultifocalinvolvementanimagingdiagnosisdilemmaandararecasereport