Tumor-associated macrophages induced spheroid formation by CCL18-ZEB1-M-CSF feedback loop to promote transcoelomic metastasis of ovarian cancer

BACKGROUND: Ovarian cancer (OvCa)-tumor-associated macrophages (TAMs) spheroids are abundantly present within ascites of high malignant patients. This study investigated the mutual interaction of OvCa cells and TAMs in the spheroids. METHODS: Three-dimensional coculture system and transwell cocultur...

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Detalles Bibliográficos
Autores principales: Long, Lingli, Hu, Yue, Long, Tengfei, Lu, Xiaofang, Tuo, Ying, Li, Yubing, Wang, Min, Ke, Zunfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718465/
https://www.ncbi.nlm.nih.gov/pubmed/34969774
http://dx.doi.org/10.1136/jitc-2021-003973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718465/
https://www.ncbi.nlm.nih.gov/pubmed/34969774
http://dx.doi.org/10.1136/jitc-2021-003973

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