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Tumor-associated macrophages induced spheroid formation by CCL18-ZEB1-M-CSF feedback loop to promote transcoelomic metastasis of ovarian cancer
BACKGROUND: Ovarian cancer (OvCa)-tumor-associated macrophages (TAMs) spheroids are abundantly present within ascites of high malignant patients. This study investigated the mutual interaction of OvCa cells and TAMs in the spheroids. METHODS: Three-dimensional coculture system and transwell cocultur...
Autores principales: | Long, Lingli, Hu, Yue, Long, Tengfei, Lu, Xiaofang, Tuo, Ying, Li, Yubing, Wang, Min, Ke, Zunfu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718465/ https://www.ncbi.nlm.nih.gov/pubmed/34969774 http://dx.doi.org/10.1136/jitc-2021-003973 |
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