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circ-Sirt1 Decelerates Senescence by Inhibiting p53 Activation in Vascular Smooth Muscle Cells, Ameliorating Neointima Formation

Vascular smooth muscle cell (VSMC) senescence is a major driver of neointimal formation. We have demonstrated that circ-Sirt1 derived from the SIRT1 gene suppressed VSMC inflammation and neointimal formation. However, the effect of circ-Sirt1 inhibiting inflammation on VSMC senescence during neointi...

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Detalles Bibliográficos
Autores principales:	Kong, Peng, Li, Chang-Lin, Dou, Yong-Qing, Cao, Li, Zhang, Xiao-Yun, Zhang, Wen-Di, Bi, Ze-Qi, Peng, Zu-Yi, Yan, An-Qi, Han, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718546/ https://www.ncbi.nlm.nih.gov/pubmed/34977164 http://dx.doi.org/10.3389/fcvm.2021.724592

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