Aged xCT-Deficient Mice Are Less Susceptible for Lactacystin-, but Not 1-Methyl-4-Phenyl-1,2,3,6- Tetrahydropyridine-, Induced Degeneration of the Nigrostriatal Pathway

The astrocytic cystine/glutamate antiporter system x(c)(–) (with xCT as the specific subunit) imports cystine in exchange for glutamate and has been shown to interact with multiple pathways in the brain that are dysregulated in age-related neurological disorders, including glutamate homeostasis, red...

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Detalles Bibliográficos
Autores principales: Bentea, Eduard, De Pauw, Laura, Verbruggen, Lise, Winfrey, Lila C., Deneyer, Lauren, Moore, Cynthia, Albertini, Giulia, Sato, Hideyo, Van Eeckhaut, Ann, Meshul, Charles K., Massie, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718610/
https://www.ncbi.nlm.nih.gov/pubmed/34975413
http://dx.doi.org/10.3389/fncel.2021.796635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718610/
https://www.ncbi.nlm.nih.gov/pubmed/34975413
http://dx.doi.org/10.3389/fncel.2021.796635

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