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Role of glyoxalase 1 in methylglyoxal detoxification–the broad player of psychiatric disorders

Methylglyoxal (MG) is a highly reactive α-ketoaldehyde formed endogenously as a byproduct of the glycolytic pathway. To remove MG, various detoxification systems work together in vivo, including the glyoxalase system, which enzymatically degrades MG using glyoxalase 1 (GLO1) and GLO2. Recently, nume...

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Detalles Bibliográficos
Autores principales:	Toriumi, Kazuya, Miyashita, Mitsuhiro, Suzuki, Kazuhiro, Tabata, Koichi, Horiuchi, Yasue, Ishida, Hiroaki, Itokawa, Masanari, Arai, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718652/ https://www.ncbi.nlm.nih.gov/pubmed/34953453 http://dx.doi.org/10.1016/j.redox.2021.102222

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