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SEC coupled with in-line multiple detectors for the characterization of an oncolytic Coxsackievirus
V937 is an oncolytic virus immunotherapy clinical drug candidate consisting of a proprietary formulation of Coxsackievirus A21 (CVA21). V937 specifically binds to and lyses cells with over-expressed ICAM-1 receptors in a range of tumor cell types and is currently in phase I and II clinical trials. I...
Autores principales: | Deng, James Z., Rustandi, Richard R., Swartz, Andrew, Shieh, Yvonne, Baker, Jack B., Vlasak, Josef, Wang, Shiyi, Loughney, John W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718657/ https://www.ncbi.nlm.nih.gov/pubmed/35024440 http://dx.doi.org/10.1016/j.omto.2021.12.009 |
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