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Targeted up-regulation of Drp1 in dorsal horn attenuates neuropathic pain hypersensitivity by increasing mitochondrial fission

Mitochondria play an essential role in pathophysiology of both inflammatory and neuropathic pain (NP), but the mechanisms are not yet clear. Dynamin-related protein 1 (Drp1) is broadly expressed in the central nervous system and plays a role in the induction of mitochondrial fission process. Spared...

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Detalles Bibliográficos
Autores principales:	Zhang, Kun-Long, Li, Shu-Jiao, Pu, Xue-Yin, Wu, Fei-Fei, Liu, Hui, Wang, Rui-Qing, Liu, Bo-Zhi, Li, Ze, Li, Kai-Feng, Qian, Nian-Song, Yang, Yan-Ling, Yuan, Hua, Wang, Ya-Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718665/ https://www.ncbi.nlm.nih.gov/pubmed/34954498 http://dx.doi.org/10.1016/j.redox.2021.102216

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