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Inhibition of GCN2 alleviates hepatic steatosis and oxidative stress in obese mice: Involvement of NRF2 regulation
The development of nonalcoholic fatty liver disease (NAFLD) is associated with increased reactive oxygen species (ROS) production. Previous observations on the contradictory roles of general control nonderepressible 2 (GCN2) in regulating the hepatic redox state under different nutritional condition...
Autores principales: | Yuan, Juntao, Yu, Zhuoran, Gao, Junling, Luo, Kai, Shen, Xiyue, Cui, Bingqing, Lu, Zhongbing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718669/ https://www.ncbi.nlm.nih.gov/pubmed/34954499 http://dx.doi.org/10.1016/j.redox.2021.102224 |
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