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IL-18-Mediated SLC7A5 Overexpression Enhances Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells via the c-MYC Pathway

Objective: To investigate the role of IL-18 in the regulation of osteogenic differentiation in human bone marrow mesenchymal stem cells (hBMSCs). Methods: To assess whether IL-18 affects the osteogenic differentiation of hBMSCs through the c-MYC/SLC7A5 axis, IL-18 dose-response and time-course exper...

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Detalles Bibliográficos
Autores principales:	Ni, Feifei, Zhang, Tao, Xiao, Wanan, Dong, Hong, Gao, Jian, Liu, YaFeng, Li, Jianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718798/ https://www.ncbi.nlm.nih.gov/pubmed/34977008 http://dx.doi.org/10.3389/fcell.2021.748831

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