VikAD, a Vika site-specific recombinase-based system for efficient and scalable helper-dependent adenovirus production

Recombinant viral vectors have become integral tools for basic in vivo research applications. Helper-dependent adenoviral (HdAd) vectors have a large packaging capacity of ∼36 kb of DNA that mediate long-term transgene expression in vitro and in vivo. The large carrying capacity of HdAd enables basi...

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Detalles Bibliográficos
Autores principales: Phillips, Stacia, Ramos, Paula Valino, Veeraraghavan, Priyadharishini, Young, Samuel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718833/
https://www.ncbi.nlm.nih.gov/pubmed/35024378
http://dx.doi.org/10.1016/j.omtm.2021.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718833/
https://www.ncbi.nlm.nih.gov/pubmed/35024378
http://dx.doi.org/10.1016/j.omtm.2021.12.001

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