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VikAD, a Vika site-specific recombinase-based system for efficient and scalable helper-dependent adenovirus production
Recombinant viral vectors have become integral tools for basic in vivo research applications. Helper-dependent adenoviral (HdAd) vectors have a large packaging capacity of ∼36 kb of DNA that mediate long-term transgene expression in vitro and in vivo. The large carrying capacity of HdAd enables basi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718833/ https://www.ncbi.nlm.nih.gov/pubmed/35024378 http://dx.doi.org/10.1016/j.omtm.2021.12.001 |