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Home-Based Therapy After Stroke Using the Hand Spring Operated Movement Enhancer (HandSOME II)

We have developed a passive and lightweight wearable hand exoskeleton (HandSOME II) that improves range of motion and functional task practice in laboratory testing. For this longitudinal study, we recruited 15 individuals with chronic stroke and asked them to use the device at home for 1.5 h per we...

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Autores principales: Casas, Rafael, Sandison, Melissa, Nichols, Diane, Martin, Kaelin, Phan, Khue, Chen, Tianyao, Lum, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719001/
https://www.ncbi.nlm.nih.gov/pubmed/34975447
http://dx.doi.org/10.3389/fnbot.2021.773477
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author Casas, Rafael
Sandison, Melissa
Nichols, Diane
Martin, Kaelin
Phan, Khue
Chen, Tianyao
Lum, Peter S.
author_facet Casas, Rafael
Sandison, Melissa
Nichols, Diane
Martin, Kaelin
Phan, Khue
Chen, Tianyao
Lum, Peter S.
author_sort Casas, Rafael
collection PubMed
description We have developed a passive and lightweight wearable hand exoskeleton (HandSOME II) that improves range of motion and functional task practice in laboratory testing. For this longitudinal study, we recruited 15 individuals with chronic stroke and asked them to use the device at home for 1.5 h per weekday for 8 weeks. Subjects visited the clinic once per week to report progress and troubleshoot problems. Subjects were then given the HandSOME II for the next 3 months, and asked to continue to use it, but without any scheduled contact with the project team. Clinical evaluations and biomechanical testing was performed before and after the 8 week intervention and at the 3 month followup. EEG measures were taken before and after the 8 weeks of training to examine any recovery associated brain reorganization. Ten subjects completed the study. After 8 weeks of training, functional ability (Action Research Arm Test), flexor tone (Modified Ashworth Test), and real world use of the impaired limb (Motor Activity Log) improved significantly (p < 0.05). Gains in real world use were retained at the 3-month followup (p = 0.005). At both post-training and followup time points, biomechanical testing found significant gains in finger ROM and hand displacement in a reaching task (p < 0.05). Baseline functional connectivity correlated with gains in motor function, while changes in EEG functional connectivity paralleled changes in motor recovery. HandSOME II is a low-cost, home-based intervention that elicits brain plasticity and can improve functional motor outcomes in the chronic stroke population.
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spelling pubmed-87190012022-01-01 Home-Based Therapy After Stroke Using the Hand Spring Operated Movement Enhancer (HandSOME II) Casas, Rafael Sandison, Melissa Nichols, Diane Martin, Kaelin Phan, Khue Chen, Tianyao Lum, Peter S. Front Neurorobot Neuroscience We have developed a passive and lightweight wearable hand exoskeleton (HandSOME II) that improves range of motion and functional task practice in laboratory testing. For this longitudinal study, we recruited 15 individuals with chronic stroke and asked them to use the device at home for 1.5 h per weekday for 8 weeks. Subjects visited the clinic once per week to report progress and troubleshoot problems. Subjects were then given the HandSOME II for the next 3 months, and asked to continue to use it, but without any scheduled contact with the project team. Clinical evaluations and biomechanical testing was performed before and after the 8 week intervention and at the 3 month followup. EEG measures were taken before and after the 8 weeks of training to examine any recovery associated brain reorganization. Ten subjects completed the study. After 8 weeks of training, functional ability (Action Research Arm Test), flexor tone (Modified Ashworth Test), and real world use of the impaired limb (Motor Activity Log) improved significantly (p < 0.05). Gains in real world use were retained at the 3-month followup (p = 0.005). At both post-training and followup time points, biomechanical testing found significant gains in finger ROM and hand displacement in a reaching task (p < 0.05). Baseline functional connectivity correlated with gains in motor function, while changes in EEG functional connectivity paralleled changes in motor recovery. HandSOME II is a low-cost, home-based intervention that elicits brain plasticity and can improve functional motor outcomes in the chronic stroke population. Frontiers Media S.A. 2021-12-17 /pmc/articles/PMC8719001/ /pubmed/34975447 http://dx.doi.org/10.3389/fnbot.2021.773477 Text en Copyright © 2021 Casas, Sandison, Nichols, Martin, Phan, Chen and Lum. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Casas, Rafael
Sandison, Melissa
Nichols, Diane
Martin, Kaelin
Phan, Khue
Chen, Tianyao
Lum, Peter S.
Home-Based Therapy After Stroke Using the Hand Spring Operated Movement Enhancer (HandSOME II)
title Home-Based Therapy After Stroke Using the Hand Spring Operated Movement Enhancer (HandSOME II)
title_full Home-Based Therapy After Stroke Using the Hand Spring Operated Movement Enhancer (HandSOME II)
title_fullStr Home-Based Therapy After Stroke Using the Hand Spring Operated Movement Enhancer (HandSOME II)
title_full_unstemmed Home-Based Therapy After Stroke Using the Hand Spring Operated Movement Enhancer (HandSOME II)
title_short Home-Based Therapy After Stroke Using the Hand Spring Operated Movement Enhancer (HandSOME II)
title_sort home-based therapy after stroke using the hand spring operated movement enhancer (handsome ii)
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719001/
https://www.ncbi.nlm.nih.gov/pubmed/34975447
http://dx.doi.org/10.3389/fnbot.2021.773477
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