Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice

BACKGROUND: The Coronavirus Disease 2019 (COVID-19) pandemic has been a great threat to global public health since 2020. Although the advance on vaccine development has been largely achieved, a strategy to alleviate immune overactivation in severe COVID-19 patients is still needed. The NLRP3 inflamm...

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Detalles Bibliográficos
Autores principales: Zeng, Jianxiong, Xie, Xiaochun, Feng, Xiao-Li, Xu, Ling, Han, Jian-Bao, Yu, Dandan, Zou, Qing-Cui, Liu, Qianjin, Li, Xiaohong, Ma, Guanqin, Li, Ming-Hua, Yao, Yong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719059/
https://www.ncbi.nlm.nih.gov/pubmed/34979342
http://dx.doi.org/10.1016/j.ebiom.2021.103803

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