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Human erythroid differentiation requires VDAC1-mediated mitochondrial clearance

Erythroblast maturation in mammals is dependent on organelle clearance throughout terminal erythropoiesis. We studied the role of the outer mitochondrial membrane protein voltage-dependent anion channel-1 (VDAC1) in human terminal erythropoiesis. We show that short hairpin (shRNA)-mediated downregul...

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Detalles Bibliográficos
Autores principales: Moras, Martina, Hattab, Claude, Gonzalez-Menendez, Pedro, Fader, Claudio M., Dussiot, Michael, Larghero, Jerome, Le Van Kim, Caroline, Kinet, Sandrina, Taylor, Naomi, Lefevre, Sophie D., Ostuni, Mariano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719069/
https://www.ncbi.nlm.nih.gov/pubmed/33406813
http://dx.doi.org/10.3324/haematol.2020.257121

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