Fusion gene detection by RNA-sequencing complements diagnostics of acute myeloid leukemia and identifies recurring NRIP1-MIR99AHG rearrangements

Identification of fusion genes in clinical routine is mostly based on cytogenetics and targeted molecular genetics, such as metaphase karyotyping, fluorescence in situ hybridization and reverse-transcriptase polymerase chain reaction. However, sequencing technologies are becoming more important in c...

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Detalles Bibliográficos
Autores principales: Kerbs, Paul, Vosberg, Sebastian, Krebs, Stefan, Graf, Alexander, Blum, Helmut, Swoboda, Anja, Batcha, Aarif M. N., Mansmann, Ulrich, Metzler, Dirk, Heckman, Caroline A., Herold, Tobias, Greif, Philipp A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719081/
https://www.ncbi.nlm.nih.gov/pubmed/34134471
http://dx.doi.org/10.3324/haematol.2021.278436

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