Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways

T-cell prolymphocytic leukemia (T-PLL) is a poor-prognostic mature T-cell malignancy. It typically presents with exponentially rising lymphocyte counts, splenomegaly, and bone marrow infiltration. Effective treatment options are scarce and a better understanding of TPLL’s pathogenesis is desirable....

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Detalles Bibliográficos
Autores principales: Braun, Till, Glaß, Markus, Wahnschaffe, Linus, Otte, Moritz, Mayer, Petra, Franitza, Marek, Altmüller, Janine, Hallek, Michael, Hüttelmaier, Stefan, Schrader, Alexandra, Herling, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719084/
https://www.ncbi.nlm.nih.gov/pubmed/33543866
http://dx.doi.org/10.3324/haematol.2020.267500

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