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BRAF V600E-mutated combined large cell neuroendocrine carcinoma and adenocarcinoma responding to targeted therapy

We present a case of combined large cell neuroendocrine carcinoma (LCNEC), harbouring a BRAF V600E mutation, which significantly benefited from BRAF-targeted therapy. A 57-year-old woman was referred to our hospital for headache and vomiting. A head MRI showed a large tumour in her brain, and a whol...

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Detalles Bibliográficos
Autores principales: Sakamoto, Tomohiro, Arai, Katsunori, Makishima, Karen, Yamasaki, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719127/
https://www.ncbi.nlm.nih.gov/pubmed/34969785
http://dx.doi.org/10.1136/bcr-2021-243295