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Insulin receptor cleavage induced by estrogen impairs insulin signaling

INTRODUCTION: Soluble insulin receptor (sIR), which is the ectodomain of insulin receptor (IR), is present in human plasma. Plasma sIR levels are positively correlated with blood glucose levels and negatively correlated with insulin sensitivity. An in vitro model of IR cleavage shows that extracellu...

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Detalles Bibliográficos
Autores principales:	Yuasa, Tomoyuki, Takata, Yasunori, Aki, Nanako, Kunimi, Kotaro, Satoh, Miki, Nii, Mari, Izumi, Yoshihiko, Otoda, Toshiki, Hashida, Seiichi, Osawa, Haruhiko, Aihara, Ken-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719150/ https://www.ncbi.nlm.nih.gov/pubmed/34969688 http://dx.doi.org/10.1136/bmjdrc-2021-002467

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