Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques

The combination of planar chromatography with desorption/ionization mass-spectrometry (MS) techniques provides chemists with unique tools for fast and simple separation of mixtures followed by the detection of analytes by the most powerful analytical method. Since its introduction in the early 1990s...

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Autores principales: Borisov, Roman, Kanateva, Anastasiia, Zhilyaev, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719418/
https://www.ncbi.nlm.nih.gov/pubmed/34976947
http://dx.doi.org/10.3389/fchem.2021.771801
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author Borisov, Roman
Kanateva, Anastasiia
Zhilyaev, Dmitry
author_facet Borisov, Roman
Kanateva, Anastasiia
Zhilyaev, Dmitry
author_sort Borisov, Roman
collection PubMed
description The combination of planar chromatography with desorption/ionization mass-spectrometry (MS) techniques provides chemists with unique tools for fast and simple separation of mixtures followed by the detection of analytes by the most powerful analytical method. Since its introduction in the early 1990s, thin-layer chromatography (TLC)/matrix-assisted mass spectrometry (MALDI) has been used for the analysis of a wide range of analytes, including natural and synthetic organic compounds. Nowadays, new desorption/ionization approaches have been developed and applied in conjunction with planar chromatography competing with MALDI. This review covers recent developments in the combination of TLC with various desorption/ionization MS methods which were made in recent several years.
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spelling pubmed-87194182022-01-01 Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques Borisov, Roman Kanateva, Anastasiia Zhilyaev, Dmitry Front Chem Chemistry The combination of planar chromatography with desorption/ionization mass-spectrometry (MS) techniques provides chemists with unique tools for fast and simple separation of mixtures followed by the detection of analytes by the most powerful analytical method. Since its introduction in the early 1990s, thin-layer chromatography (TLC)/matrix-assisted mass spectrometry (MALDI) has been used for the analysis of a wide range of analytes, including natural and synthetic organic compounds. Nowadays, new desorption/ionization approaches have been developed and applied in conjunction with planar chromatography competing with MALDI. This review covers recent developments in the combination of TLC with various desorption/ionization MS methods which were made in recent several years. Frontiers Media S.A. 2021-12-16 /pmc/articles/PMC8719418/ /pubmed/34976947 http://dx.doi.org/10.3389/fchem.2021.771801 Text en Copyright © 2021 Borisov, Kanateva and Zhilyaev. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Borisov, Roman
Kanateva, Anastasiia
Zhilyaev, Dmitry
Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques
title Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques
title_full Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques
title_fullStr Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques
title_full_unstemmed Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques
title_short Recent Advances in Combinations of TLC With MALDI and Other Desorption/Ionization Mass-Spectrometry Techniques
title_sort recent advances in combinations of tlc with maldi and other desorption/ionization mass-spectrometry techniques
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719418/
https://www.ncbi.nlm.nih.gov/pubmed/34976947
http://dx.doi.org/10.3389/fchem.2021.771801
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