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PEG-PEI/siROCK2 inhibits Aβ(42)-induced microglial inflammation via NLRP3/caspase 1 pathway

OBJECTIVES: There is an urgent need to develop therapeutic strategies to improve the treatment outcome of Alzheimer’s disease. The treatment strategy of gene therapy mediated by nanocarrier systems brings new hope for the treatment of Alzheimer’s disease. ROCK2 is involved in various pathological pr...

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Detalles Bibliográficos
Autores principales:	Liu, Yunyun, Zhang, Han, Peng, Anping, Cai, Xiaodong, Wang, YuZhou, Tang, Ke, Wu, Xiuqin, Liang, Yanran, Wang, Limin, Li, Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Cellular, Molecular and Developmental Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719500/ https://www.ncbi.nlm.nih.gov/pubmed/34874326 http://dx.doi.org/10.1097/WNR.0000000000001752

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