Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure

Recently, we reported that obese Dahl salt-sensitive leptin receptor mutant (SS(LepR)mutant) rats develop glomerular injury and progressive proteinuria prior to puberty. Moreover, this early progression of proteinuria was associated with elevations in GFR. Therefore, the current study examined wheth...

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Detalles Bibliográficos
Autores principales: Brown, Andrea K., Nichols, Alyssa, Coley, Chantell A., Ekperikpe, Ubong S., McPherson, Kasi C., Shields, Corbin A., Poudel, Bibek, Cornelius, Denise C., Williams, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719629/
https://www.ncbi.nlm.nih.gov/pubmed/34975523
http://dx.doi.org/10.3389/fphys.2021.765305

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