Cargando…

A replication study separates polymorphisms behind migraine with and without depression

The largest migraine genome-wide association study identified 38 candidate loci. In this study we assessed whether these results replicate on a gene level in our European cohort and whether effects are altered by lifetime depression. We tested SNPs of the loci and their vicinity with or without inte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Petschner, Peter, Baksa, Daniel, Hullam, Gabor, Torok, Dora, Millinghoffer, Andras, Deakin, J. F. William, Bagdy, Gyorgy, Juhasz, Gabriella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719675/ https://www.ncbi.nlm.nih.gov/pubmed/34972135 http://dx.doi.org/10.1371/journal.pone.0261477

Ejemplares similares

Biology of Perseverative Negative Thinking: The Role of Timing and Folate Intake
por: Eszlari, Nora, et al.
Publicado: (2021)

The UKB envirome of depression: from interactions to synergistic effects
por: Hullam, Gabor, et al.
Publicado: (2019)

Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene
por: Gonda, Xenia, et al.
Publicado: (2021)

Genetic effects on educational attainment in Hungary
por: Ujma, Péter P., et al.
Publicado: (2021)

Financial Stress Interacts With CLOCK Gene to Affect Migraine
por: Baksa, Daniel, et al.
Publicado: (2020)

Genetic risk of depression is different in subgroups of dietary ratio of tryptophan to large neutral amino acids
por: Bruncsics, Bence, et al.
Publicado: (2023)

A new stress sensor and risk factor for suicide: the T allele of the functional genetic variant in the GABRA6 gene
por: Gonda, Xenia, et al.
Publicado: (2017)

Significance of risk polymorphisms for depression depends on stress exposure
por: Gonda, Xenia, et al.
Publicado: (2018)

Genome-wide association analysis reveals KCTD12 and miR-383-binding genes in the background of rumination
por: Eszlari, Nora, et al.
Publicado: (2019)

Childhood Adversity Moderates the Effects of HTR2A Epigenetic Regulatory Polymorphisms on Rumination
por: Eszlari, Nora, et al.
Publicado: (2019)

Inflammation and Blood-Brain Barrier in Depression: Interaction of CLDN5 and IL6 Gene Variants in Stress-Induced Depression
por: Gal, Zsofia, et al.
Publicado: (2022)

Every Night and Every Morn: Effect of Variation in CLOCK Gene on Depression Depends on Exposure to Early and Recent Stress
por: Gyorik, Dorka, et al.
Publicado: (2021)

P2RX7 gene variation mediates the effect of childhood adversity and recent stress on the severity of depressive symptoms
por: Kristof, Zsuliet, et al.
Publicado: (2021)

Inflamed Mind: Multiple Genetic Variants of IL6 Influence Suicide Risk Phenotypes in Interaction With Early and Recent Adversities in a Linkage Disequilibrium-Based Clumping Analysis
por: Bokor, Janos, et al.
Publicado: (2021)

Sex Differences of Periaqueductal Grey Matter Functional Connectivity in Migraine
por: Gecse, Kinga, et al.
Publicado: (2021)

“Out, out, brief candle! Life’s but a walking shadow”: 5-HTTLPR Is Associated With Current Suicidal Ideation but Not With Previous Suicide Attempts and Interacts With Recent Relationship Problems
por: Bokor, Janos, et al.
Publicado: (2020)

Variability in the Effect of 5-HTTLPR on Depression in a Large European Population: The Role of Age, Symptom Profile, Type and Intensity of Life Stressors
por: Juhasz, Gabriella, et al.
Publicado: (2015)

Catenin Alpha 2 May Be a Biomarker or Potential Drug Target in Psychiatric Disorders with Perseverative Negative Thinking
por: Eszlari, Nora, et al.
Publicado: (2021)

Increased activation of the pregenual anterior cingulate cortex to citalopram challenge in migraine: an fMRI study
por: Edes, Andrea Edit, et al.
Publicado: (2019)

Inter-individual differences in pain anticipation and pain perception in migraine: Neural correlates of migraine frequency and cortisol-to-dehydroepiandrosterone sulfate (DHEA-S) ratio
por: Kökönyei, Gyöngyi, et al.
Publicado: (2021)

Variation along P2RX7 interacts with early traumas on severity of anxiety suggesting a role for neuroinflammation
por: Kristof, Zsuliet, et al.
Publicado: (2023)

Association of plasma tryptophan concentration with periaqueductal gray matter functional connectivity in migraine patients
por: Gecse, Kinga, et al.
Publicado: (2022)

Interleukin-6 promoter polymorphism interacts with pain and life stress influencing depression phenotypes
por: Kovacs, David, et al.
Publicado: (2016)

Decreased Openness to Experience Is Associated with Migraine-Type Headaches in Subjects with Lifetime Depression
por: Magyar, Mate, et al.
Publicado: (2017)

Perceived stress in the time of COVID-19: the association with brooding and COVID-related rumination in adults with and without migraine
por: Kovács, Lilla Nóra, et al.
Publicado: (2021)

Circadian Variation of Migraine Attack Onset Affects fMRI Brain Response to Fearful Faces
por: Baksa, Daniel, et al.
Publicado: (2022)

Effects of Different Stressors Are Modulated by Different Neurobiological Systems: The Role of GABA-A Versus CB1 Receptor Gene Variants in Anxiety and Depression
por: Gonda, Xenia, et al.
Publicado: (2019)

“… wise, amazed, temp’rate, and furious, Loyal and neutral, in a moment”: first heritability analysis of affective temperaments reports remarkably high SNP-based heritability
por: Gonda, X., et al.
Publicado: (2023)

Antidepressant treatment response is modulated by genetic and environmental factors and their interactions
por: Kovacs, Dávid, et al.
Publicado: (2014)

Downregulation of the Vitamin D Receptor Regulated Gene Set in the Hippocampus After MDMA Treatment
por: Petschner, Peter, et al.
Publicado: (2018)

Rumination in migraine: Mediating effects of brooding and reflection between migraine and psychological distress
por: Kokonyei, Gyongyi, et al.
Publicado: (2016)

Depressive symptoms are correlated with periaqueductal gray matter functional connectivity in migraine
por: Gecse, K., et al.
Publicado: (2022)

The Genetic Underpinnings of Affective Temperaments: Identifying Novel Risk Variants with a Whole Genome Analytical Approach
por: Gonda, X., et al.
Publicado: (2022)

Association of genetic variants of Glutamate Metabotropic Receptor 5 gene and state-anhedonia
por: Török, D., et al.
Publicado: (2022)

Comorbidities in the diseasome are more apparent than real: What Bayesian filtering reveals about the comorbidities of depression
por: Marx, Peter, et al.
Publicado: (2017)

Transcriptional Evidence for the Role of Chronic Venlafaxine Treatment in Neurotrophic Signaling and Neuroplasticity Including also Glutatmatergic- and Insulin-Mediated Neuronal Processes
por: Tamási, Viola, et al.
Publicado: (2014)

Biomarkers for personalised treatment in psychiatric diseases
por: Bagdy, Gyorgy, et al.
Publicado: (2013)

Spontaneous migraine attack causes alterations in default mode network connectivity: a resting-state fMRI case report
por: Edes, Andrea Edit, et al.
Publicado: (2017)

Circadian Variation of Migraine Attack Onset: A Review of Clinical Studies
por: Baksa, Daniel, et al.
Publicado: (2019)

Regular Practice of Autogenic Training Reduces Migraine Frequency and Is Associated With Brain Activity Changes in Response to Fearful Visual Stimuli
por: Dobos, Dóra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ukc8j04v1ms309cj5cp0p66qi5