MHC class I antigen cross-presentation mediated by PapMV nanoparticles in human antigen-presenting cells is dependent on autophagy

Nanoparticles made of the coat protein of papaya mosaic virus (PapMV) and a single-strand RNA were previously shown to be an efficient antigen presentation system for the trigger of cellular immunity. Engineering of PapMV nano with a cytotoxic T lymphocyte epitope was previously shown activating spe...

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Detalles Bibliográficos
Autores principales: Possamaï, David, Hanafi, Laïla-Aïcha, Bellemare-Pelletier, Angélique, Hamelin, Katia, Thébault, Paméla, Hébert, Marie-Josée, Gagnon, Étienne, Leclerc, Denis, Lapointe, Réjean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719699/
https://www.ncbi.nlm.nih.gov/pubmed/34972158
http://dx.doi.org/10.1371/journal.pone.0261987

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