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CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis

Proper cilia formation in multiciliated cells (MCCs) is necessary for appropriate embryonic development and homeostasis. Multicilia share many structural characteristics with monocilia and primary cilia, but there are still significant gaps in our understanding of the regulation of multiciliogenesis...

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Detalles Bibliográficos
Autores principales: Lee, Moonsup, Nagashima, Kunio, Yoon, Jaeho, Sun, Jian, Wang, Ziqiu, Carpenter, Christina, Lee, Hyun-Kyung, Hwang, Yoo-Seok, Westlake, Christopher J., Daar, Ira O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719716/
https://www.ncbi.nlm.nih.gov/pubmed/34787650
http://dx.doi.org/10.1083/jcb.202102110

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