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CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis
Proper cilia formation in multiciliated cells (MCCs) is necessary for appropriate embryonic development and homeostasis. Multicilia share many structural characteristics with monocilia and primary cilia, but there are still significant gaps in our understanding of the regulation of multiciliogenesis...
Autores principales: | Lee, Moonsup, Nagashima, Kunio, Yoon, Jaeho, Sun, Jian, Wang, Ziqiu, Carpenter, Christina, Lee, Hyun-Kyung, Hwang, Yoo-Seok, Westlake, Christopher J., Daar, Ira O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719716/ https://www.ncbi.nlm.nih.gov/pubmed/34787650 http://dx.doi.org/10.1083/jcb.202102110 |
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