Identification of a distal RXFP1 gene enhancer with differential activity in fibrotic lung fibroblasts involving AP-1

Relaxin/insulin-like family peptide receptor 1 (RXFP1) mediates relaxin’s antifibrotic effects and has reduced expression in the lung and skin of patients with fibrotic interstitial lung disease (fILD) including idiopathic pulmonary fibrosis (IPF) and systemic sclerosis (SSc). This may explain the f...

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Detalles Bibliográficos
Autores principales: Chen, Ting-Yun, Li, Xiaoyun, Goobie, Gillian C., Hung, Ching-Hsia, Hung, Tin-Kan, Hamilton, Kyle, Bahudhanapati, Harinath, Tan, Jiangning, Kass, Daniel J., Zhang, Yingze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719731/
https://www.ncbi.nlm.nih.gov/pubmed/34972106
http://dx.doi.org/10.1371/journal.pone.0254466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719731/
https://www.ncbi.nlm.nih.gov/pubmed/34972106
http://dx.doi.org/10.1371/journal.pone.0254466

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