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Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen

The innate immune system detects pathogens and initiates adaptive immune responses. Inflammasomes are central components of the innate immune system, but whether inflammasomes provide sufficient signals to activate adaptive immunity is unclear. In intestinal epithelial cells (IECs), inflammasomes ac...

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Detalles Bibliográficos
Autores principales:	Deets, Katherine A, Nichols Doyle, Randilea, Rauch, Isabella, Vance, Russell E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719880/ https://www.ncbi.nlm.nih.gov/pubmed/34939932 http://dx.doi.org/10.7554/eLife.72082

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