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Hyperosmolarity adversely impacts recombinant protein synthesis by Yarrowia lipolytica—molecular background revealed by quantitative proteomics

ABSTRACT: In this research, we were interested in answering a question whether subjecting a Yarrowia lipolytica strain overproducing a recombinant secretory protein (rs-Prot) to pre-optimized stress factors may enhance synthesis of the rs-Prot. Increased osmolarity (3 Osm kg(−1)) was the primary str...

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Detalles Bibliográficos
Autores principales:	Kubiak-Szymendera, Monika, Skupien-Rabian, Bozena, Jankowska, Urszula, Celińska, Ewelina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Genomics, Transcriptomics, Proteomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720085/ https://www.ncbi.nlm.nih.gov/pubmed/34913994 http://dx.doi.org/10.1007/s00253-021-11731-y

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