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Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery
Latex, a milky substance found in a variety of plants which is a natural source of biologically active compounds. In this study, Latex was collected from raw Carica papaya and was characterized using UV–Vis, FTIR and GC–MS analyses. Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) were synthesiz...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720089/ https://www.ncbi.nlm.nih.gov/pubmed/34972829 http://dx.doi.org/10.1038/s41598-021-03328-2 |
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author | Samrot, Antony V. Saigeetha, S. Mun, Chua Yeok Abirami, S. Purohit, Kajal Cypriyana, P. J. Jane Dhas, T. Stalin Inbathamizh, L. Kumar, S. Suresh |
author_facet | Samrot, Antony V. Saigeetha, S. Mun, Chua Yeok Abirami, S. Purohit, Kajal Cypriyana, P. J. Jane Dhas, T. Stalin Inbathamizh, L. Kumar, S. Suresh |
author_sort | Samrot, Antony V. |
collection | PubMed |
description | Latex, a milky substance found in a variety of plants which is a natural source of biologically active compounds. In this study, Latex was collected from raw Carica papaya and was characterized using UV–Vis, FTIR and GC–MS analyses. Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) were synthesized, coated with C. papaya latex (PL-Sp) and characterized using UV–Vis, FT-IR, SEM–EDX, XRD, VSM and Zeta potential analyses. SPIONs and latex coated SPIONs (PL-Sp) were used in batch adsorption study for effective removal of Methylene blue (MB) dye, where (PL-Sp) removed MB dye effectively. Further the PL-Sp was used to produce a nanoconjugate loaded with curcumin and it was characterized using UV–Vis spectrophotometer, FT-IR, SEM–EDX, XRD, VSM and Zeta potential. It showed a sustained drug release pattern and also found to have good antibacterial and anticancer activity. |
format | Online Article Text |
id | pubmed-8720089 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-87200892022-01-05 Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery Samrot, Antony V. Saigeetha, S. Mun, Chua Yeok Abirami, S. Purohit, Kajal Cypriyana, P. J. Jane Dhas, T. Stalin Inbathamizh, L. Kumar, S. Suresh Sci Rep Article Latex, a milky substance found in a variety of plants which is a natural source of biologically active compounds. In this study, Latex was collected from raw Carica papaya and was characterized using UV–Vis, FTIR and GC–MS analyses. Super Paramagnetic Iron Oxide Nanoparticles (SPIONs) were synthesized, coated with C. papaya latex (PL-Sp) and characterized using UV–Vis, FT-IR, SEM–EDX, XRD, VSM and Zeta potential analyses. SPIONs and latex coated SPIONs (PL-Sp) were used in batch adsorption study for effective removal of Methylene blue (MB) dye, where (PL-Sp) removed MB dye effectively. Further the PL-Sp was used to produce a nanoconjugate loaded with curcumin and it was characterized using UV–Vis spectrophotometer, FT-IR, SEM–EDX, XRD, VSM and Zeta potential. It showed a sustained drug release pattern and also found to have good antibacterial and anticancer activity. Nature Publishing Group UK 2021-12-31 /pmc/articles/PMC8720089/ /pubmed/34972829 http://dx.doi.org/10.1038/s41598-021-03328-2 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Samrot, Antony V. Saigeetha, S. Mun, Chua Yeok Abirami, S. Purohit, Kajal Cypriyana, P. J. Jane Dhas, T. Stalin Inbathamizh, L. Kumar, S. Suresh Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery |
title | Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery |
title_full | Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery |
title_fullStr | Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery |
title_full_unstemmed | Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery |
title_short | Utilization of Carica papaya latex on coating of SPIONs for dye removal and drug delivery |
title_sort | utilization of carica papaya latex on coating of spions for dye removal and drug delivery |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720089/ https://www.ncbi.nlm.nih.gov/pubmed/34972829 http://dx.doi.org/10.1038/s41598-021-03328-2 |
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