Mitochondrial calcium uniporter deletion prevents painful diabetic neuropathy by restoring mitochondrial morphology and dynamics

Painful diabetic neuropathy (PDN) is an intractable complication affecting 25% of diabetic patients. Painful diabetic neuropathy is characterized by neuropathic pain accompanied by dorsal root ganglion (DRG) nociceptor hyperexcitability, resulting in calcium overload, axonal degeneration, and loss o...

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Detalles Bibliográficos
Autores principales: George, Dale S., Hackelberg, Sandra, Jayaraj, Nirupa D., Ren, Dongjun, Edassery, Seby L., Rathwell, Craig A., Miller, Rachel E., Malfait, Anne-Marie, Savas, Jeffrey N., Miller, Richard J., Menichella, Daniela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720329/
https://www.ncbi.nlm.nih.gov/pubmed/34232927
http://dx.doi.org/10.1097/j.pain.0000000000002391

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